Automating the T-SPOT.TB test

In TB testing, why trade accuracy for efficiency when you don’t have to?

The T-SPOT®.TB test is now automated using the T-Cell SelectTM reagent kit which provides a simplified workflow while maintaining the same superior clinical performance you can expect from the T-SPOT.TB test. 1,2

The T-SPOT.TB test with the T-Cell Select reagent kit provides you with:

  • Superior clinical performance 1,2
  • Reduced hands-on time
  • Extended blood sample stability
  • Improved blood sample logistics
  • Maximized operational efficiency
  • Customizable and scalable solutions

What is T-Cell Select?
T-Cell Select is a peripheral blood mononuclear cell isolation reagent that uses positive selection of targeted immune cells with magnetic bead-based cell separation to automate and simplify the preparation of cells for the T-SPOT.TB test.

Laboratories T-SPOT.TB test male

Simplified workflow using magnetic bead-based cell separation to quickly isolate targeted immune cells

Reduces hands-on time

Automation of the T-SPOT.TB test has been shown to reduce hands-on time as much as 50% in European laboratories, depending on what components of the modular system are used.

Reduce hands-on time as much as 50%
Increase sample throughput without increasing the number of technicians
Free up technicians for other laboratory tasks

Allows for scalability

By choosing to automate just one, a number, or all of the processes within the T-SPOT.TB test workflow, you can select the most cost-effective solution for your specific needs.

Low throughput automation
solution for cell isolation: KingFisher FlexTM

Up to 24 samples. Consumables: 24-well Deep Well Plate (DWP) for samples and reagents, magnetic tip rod. Footprint: 28 kgs 680 mm x 600 mm x 380 mm (W x D x H).


Uncompromising accuracy for immunocompromised patients

Automation of the T-SPOT.TB test makes the clinically superior IGRA1,2 accessible to more physicians who treat vulnerable immunocompromised patients.

Patient and nurse
  1. Maintains superior clinical performance

    The step the T-Cell Select reagent kit automates plays a key role in maintaining the clinical performance of the T-SPOT.TB test even in challenging to diagnose populations like the immunocompromised3

  2. Displays superior sensitivity

    The ATS/IDSA/CDC guidelines state that the T-SPOT.TB test displays superior sensitivity (90 – 95 %) to the TST (71 – 81 %) and the QFT®-GIT test (81 – 86 %)2

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Don’t rely on processes outside your lab.
Take control with improved blood sample stability and logistics

Samples stored at room temperature for 54 hours

Enables easy centralization of sample processing and further simplifies sample logistics.

  • Flexibility for sample batching
  • Simplify sample delivery​
  • Extend sample delivery
  • Expand the reach of your laboratory

Simple sample logistics using routine phlebotomy

Ensure all up-front processing of the specimen after blood draw is done in a laboratory setting where controlled conditions are leveraged to mitigate the impact of confounding variables.

Sources of IGRA variability4,5T-SPOT.TBOther IGRAs
Specialized tubesNoYes
On-site refrigeration NoYes
On-site incubationNoYes
Shaking of blood tubesNoYes
Blood volume variabilityNoYes

The only commercially available IGRA appropriate to be submitted under CPT® code 86481

CPT Code86481
Applicable testThe T-SPOT.TB test
DescriptionTuberculosis test, cell mediated immunity antigen response measurement; enumeration of gamma interferon-producing T-cells in cell suspension

Contact us today to learn more about automating the T-SPOT.TB test

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