The TB test for children

The T-SPOT.TB test is the only IGRA cleared by the United States Food and Drug Administration (FDA) for your patients two and older, including your BCG-vaccinated patients, healthy patients and patients with compromised immune systems.1

For everyone over the age of two

Only IGRA cleared by FDA for ages two and up1

When it comes to children, you know that not all diagnostic tests have the same accuracy in pediatric populations as they do in adults. Fortunately, the T-SPOT.TB test is reliable for not only the healthy children you test, but also for the children that have medical issues such as diabetes, are on a corticosteroid, have rheumatological, gastrointestinal, dermatological issues, renal issues, HIV, and any other medical diagnosis that suppresses their immune system.

Did you know?
The T-SPOT.TB test is also the only interferon-gamma release assay (IGRA) without a warning or limitation in its package insert for screening immunocompromised patients.1,2


  1. Easy1

    The younger the patient, the smaller the blood sample

  2. Accurate1

    The only TB test with both sensitivity and specificity exceeding 95% and no cross-reaction with the BCG-vaccine

  3. Accessible

    Available through all Quest Diagnostics® Patient Service Centers and numerous regional laboratory partners

Doctor with Ipad

A moment of truth

As a healthcare provider, your goal is to offer your pediatric patients a reliable tuberculosis (TB) test. The T-SPOT.TB test is that test. By counting the cells, it mitigates the risk that low cell count will impact patient results.3 Cells are washed to prevent interference from substances or contaminants and then counted to ensure that a standard number of cells, 1 million, are used in the assay.1 You need an answer you can trust. An accurate TB test along with your clinical evaluation of the patient will give you that answer, and a moment of truth you can count on.

Reduce unnecessary return visits and treatments

  • In a study of > 3,600 children under the age of 15, switching from the tuberculin skin test (TST) to an IGRA could reduce unnecessary chest x-rays and treatments by up to two-thirds in non-US born children.4
  • In study of over > 645,000 samples, the T-SPOT.TB test had an invalid rate of < 1%.5

1 tube, 1 visit and low blood volume requirements1

  • Children 10 years old and over: 1 sodium or lithium heparin 6 mL tube
  • Children > 2 or < 10 years old: 1 sodium or lithium heparin 4 mL tube
  • Children up to 2 years old: 1 sodium or lithium heparin 2 mL pediatric tube*

    Did you know?
    Samples can be drawn using a butterfly needle without the use of a purge tube. Many butterfly needles have the same needle gauge as a TST.6

Guidelines support IGRA testing

GuidelineRecommendation by population
American Academy of Pediatrics (AAP) 20187IGRAs are indicated in ages 2 and up, and preferred in children who are BCG-vaccinated or unlikely to return to have TST read
Infectious Diseases Society of America (IDSA), American Thoracic Society (ATS) and Centers for Disease Control (CDC), 20178Ages 5 and up, IGRAs indicated, especially in those who are not high risk for progressing to active TB
CDC Civil Surgeons 20189IGRAs required in ages 2 and up
– All applicants 2 years or older must have an IGRA
– TST cannot be used as a substitute for IGRA testing

Learn more about the
T-SPOT.TB test

Get Started